Cornersville (12-3, 5-0 District) buried the Lady Wildcats early and forged a 26-10 lead in the first half before opening up a 45-19 advantage late in the fourth quarter en route claiming the 20-point win.
CHS turned in one of their best defensive performances of the season and limited Santa Fe (3-11, 2-3 District) to a mere eight field goals on 18 percent shooting, which included a 3-of-21 effort from three-point range.
Aided by a 5-of-7 shooting performance in the third quarter, the Lady Bulldogs shot 39 percent (16-of-41) from the floor despite hitting only 1-of-10 attempts from beyond the arc.
Cornersville did commit three more turnovers (17-14) than the Lady Wildcats, but outrebounded Santa Fe 34-22 and held a 12-9 edge on the offensive glass.
"I thought we came out of the chute and played well. We played hard and had some good individual performances," said CHS coach Micah Landers. "Overall this wasn't one of our best offensive games, but we played good defense and handcuffed them. We held them to 19 points before we subbed out, which is pretty impressive to me because they have a couple of girls in Baylee Hemphill and Allison Pack that have hurt us in the past."
Hemphill, Allie Lusk, and Mary Troy each notched six points to pace Santa Fe.
The Lady Bulldogs took control of the game right from the start and raced out to a 15-4 lead late in the first quarter with the help of four points from Ashley Umbles and baskets from Holt, Brittany Umbles, Rogers, Stacey, and Stewart.
Lusk hit a trey in the waning moments of the first period to narrow the gap to 15-7, but Cornersville put together a 9-0 run behind four points from Brittany Umbles, three Holt free throws, and a runner by Rogers to open up a 24-7 advantage with 2:26 left in the second quarter.
After Lusk made another three to cut the deficit to 24-10, Ashley Umbles scored on a layup to give CHS a 26-10 lead at the break before CHS tallied the first four points of the third period thanks to a jumper by Ashley Umbles and a Holt runner to make it 30-10.
Hemphill notched four straight points on a trey and a free throw to close the gap to 30-14, but the Lady Bulldogs promptly rattled off seven consecutive points on the strength of a Ashley Umbles layup, a jumper by Rogers, and a Holt three to push their lead to 37-14 late in the third quarter.
Santa Fe tallied the next four points to trim the deficit to 37-18 at the end of the third period, before Cornersville responded with an 8-1 spurt, highlighted by layups from Ashley Umbles and Welch, to forge a 45-19 advantage with 1:36 left in the fourth quarter.
The Lady Wildcats then scored the final six points of the game for the 45-25 final.